Jane Vasco with the help of a new covert government unit must track down and contain the spread of "Neuros," genetically altered humans with extraordinary powers.
When military stockpiles start to go missing before a presidential visit, Jane and the team are forced into high alert. Meanwhile, Jane confronts a Neuro with the ability to control the dead.
A Neuro with the ability to steal memory and knowledge preys on Riley putting the security of the entire operation in jeopardy.
A Neuro who can see the future warns Jane and the team of their impending death on the day they arrest him. Meanwhile, the team is disturbed by the psychic's purchases
When inhabitants of an FBI safe house start to experience unexplained dreams and visions, Jane and crew must investigate potential Neuro activity.
While investigating psychiatric patients who share the same unusual nightmare, Jane and Maureen suspect a Neuro has the ability to use nightmares as weapons.
The team investigate the suicides of individuals placed in witness protection and discover a Neuro who is capable of creating hallucinations.
Awakening in a hospital Jane learns that she murdered Riley. Meanwhile, Maureen investigates a doctor researching Neuros.
Connor is arrested for arson and murder while out hunting for a Neuro, which is believed to have started numerous house fires.
A young woman suddenly ages overnight, Jane and Maureen go undercover to find the cause.
Connor suffers a series of unfortunate events, believing it to be coincidental. However, he learns that members of his former police squad have died of strange causes.
Jane and Connor go undercover in a small town, posed as a married couple, after a federal agent's disappearance prompts an investigation.
An investigation is started after Neuros begin to die before the team can apprehend them.
Howie is a magician who can miraculously perform the impossible, which prompts Riley to begin an investigation into possible Neuro activity.
Sabotage hinders Jane's efforts to catch a Neuro, she becomes suspicious of a faith healer that she has been visiting.
Jane seeks help from a Neuro after Brian (Jane's boyfriend) and Joe forget who she is, the Neuro has the ability to remove and store memories within his mind.
A Neuro causes the team to become stuck in a timeloop, causing them to relive the same day repeatedly. Meanwhile, the Neuro who caused the timeloop tries to finish an assassination.
Jane discovers the disturbing truth about her abilities while searching for a Neuro who escaped the team.
The team respond when several incarcerated Neuros revolt and launch a prison break.
The residents of a small village are plagued by an invisible presence which is attacking and murdering the villagers.
Andre encounters a Neuro from his past that was chipped, but he learns that she has regained her abilities and she has a grudge.
Several dangerous Neuros launch a prison break after an emergency at NICO.